Reclone Publications
Reports & Press
The Reagent Collaboration Network (Reclone) seeks to address the global asymmetry in research and development in biotechnology across the Global South through open sharing of biomaterials, protocols and knowledge. The end goal is to build an international community enabling more sustainable, equitable and decentralized reagent manufacturing. The initiative works through regional distribution hubs and nodes to provide local access to resources and expertise in reagent manufacturing.
Global access to diagnostics is constrained not only by the availability of testing technologies but also by their dependence on costly supply chains that typically originate from a small number of capital-intensive biotechnology hubs. Here, we argue that integrating decentralized diagnostics with local manufacturing and research capacity is essential to building resilient, equitable and sustainable diagnostic ecosystems.
Through training, partnerships, and community exchange, Reclone advanced technical expertise, fostered open science practices, and grew its international presence. The milestones highlighted in this report reflect a year of collective progress toward a more equitable and resilient global biotechnology ecosystem.
Reclone’s Vision and Missions as presented at the Synthetic Biology UK conference in Nov-2024, with updates on the Open DNA Collection, the Reclone Assembly Syntax, and how you can get involved.
A status update on sharing biological tools and a collective vision for how open biosharing could disrupt and drastically improve the bioeconomy and our biotech research and innovation ecosystem (Jul-2024).
Academic Publications
The following papers used Reclone community resources and/or the Open DNA Collections distributed by Free Genes and Reclone members.
International multisite implementation of distributed cell-free protein biomanufacturing to advance health and research equity
Severino Jefferson Ribeiro da Silva, Quinn Matthews, Séverine Cazaux, Justin R. J. Vigar, Bárbara N. R. Santos, Deyse C. M. Carvalho, Lauren A. Cranmer, David Duplat, Serena Singh, Mohammad Simchi, Paula Benítez-Bolivar, Thaíse Yasmine Vasconcelos de Lima Cavalcanti, Kaiyue Wu, Renata P. G. Mendes, Tanvi Kale, Ana L. L. Divarzak, Kristof Bozovicar, Jennifer Doucet, Anibal Arce, Cielo Léon, Valentina Ferrando, Jessica Nguyen, Anson Ho, Suelen C. de Lima, Pouriya Bayat, Yuxiu Guo, Seray Cicek, Aidan Tinafar, Larissa Krokovsky, Laís C. Machado, Ashyad Rayhan, Idorenyin A. Iwe, Alexander Klenov, Thiago P. G. de Araujo, Jean P. M. Nascimento, Jurandy J. F. Magalhães, Marcela Guevara-Suarez, Patricia Garcia Canete, Kodjo Ayi, Moiz Charania, Tara E. Stehelin, Kate Chatfield-Reed, Marcelo H. S. Paiva, Ian Crandall, Mazzulli Gabriel da Luz Wallau, Abelardo Silva-Júnior, Adriana Bernal, Chaitanya A. Athale, Alexander A. Green, Scott C. Weaver, Camila González, Fernán Federic, Lindomar Pena, Keith Pardee
An open one-step RT-qPCR for SARS-CoV-2 detection
Ariel Cerda, Maira Rivera, Grace Armijo, Catalina Ibarra-Henriquez, Javiera Reyes, Paula Blázquez-Sánchez, Javiera Avilés, Aníbal Arce, Aldo Seguel, Alexander J Brown, Yesseny Vásquez, Marcelo Cortez-San Martín, Francisco A Cubillos, Patricia García, Marcela Ferres, César A Ramírez-Sarmiento, Fernán Federici, Rodrigo A Gutiérrez
[Preprint] Open Educational Resources for distributed hands-on teaching in molecular biology
Ariel Cerda Rojas, Alejandro Aravena, Anibal Arce, Valentina Zapata, Wladimir Araya, Domingo Gallardo, Javiera Aviles, Francisco Quero, Isaac Nunez, Tamara Matute, Felipe Navarro, Valentina Ferrando, Marta Blanco, Sebastian Velozo, Sebastian Aguilera, Francisco Chateau, Jennifer C Molloy, Guy Aidelberg, Ariel B Lindner, Fernando Castro, Pablo Cremades, Cesar A Ramirez-Sarmiento, Fernan Federici
Homebrew reagents for low-cost RT-LAMP
Tamara Matute, Isaac Nuñez, Maira Rivera, Javiera Reyes, Paula Blázquez-Sánchez, Aníbal Arce, Alexander J Brown, Chiara Gandini, Jennifer Molloy, César A Ramirez-Sarmiento, Fernán Federici
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